Jianzhong Chen Selected Research

Tacrolimus Binding Proteins (FKBP)

4/2020

Binding modes and conformational changes of FK506-binding protein 51 induced by inhibitor bindings: insight into molecular mechanisms based on multiple simulation technologies.

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Jianzhong Chen Research Topics

Disease

31	Neoplasms (Cancer) 12/2023 - 08/2007
7	Neoplasm Metastasis (Metastasis) 01/2021 - 06/2013
5	Alzheimer Disease (Alzheimer's Disease) 06/2023 - 10/2013
4	Inflammation (Inflammations) 01/2022 - 08/2018
4	Obesity 01/2019 - 09/2016
3	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 01/2015
3	Dry Eye Syndromes (Dry Eye Syndrome) 01/2021 - 01/2017
3	Prostatic Neoplasms (Prostate Cancer) 04/2020 - 05/2014
2	Retinal Detachment (Retinal Detachments) 01/2024 - 01/2022
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 02/2023 - 09/2016
2	Type 2 Diabetes Mellitus (MODY) 02/2023 - 06/2022
2	Stroke (Strokes) 02/2023 - 01/2021
2	Diabetic Nephropathies (Diabetic Nephropathy) 06/2022 - 01/2017
2	Cholangiocarcinoma 01/2021 - 01/2019
2	Insulin Resistance 01/2021 - 01/2020
2	Circulating Neoplastic Cells 01/2017 - 03/2014
2	Melanoma (Melanoma, Malignant) 03/2016 - 04/2015
2	Carcinoma (Carcinomatosis) 05/2015 - 05/2014
1	Breast Cyst 01/2024
1	Infections 10/2023
1	Heart Diseases (Heart Disease) 02/2023
1	COVID-19 09/2022
1	Retinal Diseases 01/2022
1	Reperfusion Injury 01/2022
1	Familial Amyloidosis (Hereditary Amyloidosis) 01/2022
1	Macular Degeneration (Age-Related Maculopathy) 01/2022
1	Liver Neoplasms (Liver Cancer) 01/2022
1	Asthma (Bronchial Asthma) 01/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 12/2021
1	Hypercholesterolemia 12/2021
1	Hyperlipidemias (Hyperlipidemia) 12/2021
1	Dysbiosis 01/2021
1	Ischemic Stroke 01/2021
1	Thrombosis (Thrombus) 01/2021
1	Renal Insufficiency (Renal Failure) 01/2021
1	Acute Kidney Injury (Acute Renal Failure) 01/2021
1	Fatigue 12/2020
1	Ankylosing Spondylitis 10/2019

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 10/2023 - 08/2007
7	EnzymesIBA 06/2023 - 05/2014
6	LipidsIBA 01/2024 - 01/2017
6	Mifepristone (RU 486)FDA Link 05/2018 - 03/2014
5	Glucose (Dextrose)FDA LinkGeneric 02/2023 - 05/2014
5	Ursolic AcidIBA 03/2017 - 05/2014
4	Amyloid (Amyloid Fibrils)IBA 06/2023 - 10/2019
4	metapristoneIBA 12/2017 - 03/2014
3	Biomarkers (Surrogate Marker)IBA 10/2019 - 04/2015
2	CreatinineIBA 06/2022 - 01/2017
2	AlbuminsIBA 06/2022 - 01/2017
2	Therapeutic UsesIBA 01/2022 - 01/2015
2	mirabegronIBA 01/2021 - 01/2020
2	ApolipoproteinsIBA 01/2021 - 08/2007
2	Anaplastic Lymphoma KinaseIBA 12/2020 - 11/2017
2	Fatty Acid-Binding ProteinsIBA 01/2019 - 08/2018
2	Abortifacient Agents (Abortifacients)IBA 01/2017 - 01/2016
2	ProdrugsIBA 04/2015 - 04/2015
2	Deoxyglucose (2 Deoxy D glucose)IBA 01/2015 - 05/2014
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2015 - 05/2014
2	Adenosine Triphosphate (ATP)IBA 01/2015 - 05/2014
2	GlucokinaseIBA 01/2015 - 05/2014
1	GelatinIBA 01/2024
1	AgarIBA 01/2024
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 12/2023
1	human ACE2 proteinIBA 10/2023
1	bis(1,3-dichloropropyl)phosphateIBA 02/2023
1	Antiviral Agents (Antivirals)IBA 09/2022
1	CA-72-4 antigenIBA 06/2022
1	Guanosine Triphosphate (GTP)IBA 01/2022
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2022
1	InflammasomesIBA 01/2022
1	resiquimodIBA 01/2022
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2022
1	PlasticsIBA 12/2021
1	O,O'- dimethyl- O- (6- chlorobicyclo(3.2.0)heptadiene- 1,5- yl)phosphateIBA 12/2021
1	CeramidesIBA 12/2021
1	Endocrine DisruptorsIBA 12/2021
1	Volatile Fatty AcidsIBA 01/2021
1	Vancomycin FDA LinkGeneric 01/2021
1	Acetates (Acetic Acid Esters)FDA Link 01/2021
1	Immune Checkpoint InhibitorsIBA 01/2021
1	Furosemide (Lasix)FDA LinkGeneric 01/2021
1	Apolipoproteins B (ApoB)IBA 01/2021
1	Pioglitazone (Actos)FDA Link 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	carbon fiber reinforced plastic (carbon-fibre reinforced plastic)IBA 12/2020
1	Carbon Fiber (Grafil)IBA 12/2020
1	SteroidsIBA 04/2020
1	Hormones (Hormone)IBA 04/2020
1	Tacrolimus Binding Proteins (FKBP)IBA 04/2020
1	Hemoglobins (Hemoglobin)IBA 01/2020
1	N-caproylsphingosineIBA 01/2020
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2020
1	InterleukinsIBA 10/2019

Therapy/Procedure

7	Therapeutics 01/2022 - 06/2013
2	Immunotherapy 01/2022 - 01/2021
2	Chemoprevention 01/2017 - 09/2014
2	Oral Administration 03/2016 - 04/2015
1	Liver Transplantation 01/2022
1	Radiofrequency Ablation 01/2022
1	Thrombectomy 01/2021